A. High Hemoglobin Concentration
B. High Oxygen Concentration
C. Inability to bind 2,3 DPG
D. All of the above
Ans:C. Inability to bind 2,3 DPG
Oxygen Dissociation Curve of Maternal versus Fetal is shown in the image.
- Fetal Hemoglobin has higher affinity to O2 so as to obtain O2 from maternal blood in the placenta.
- The high oxygen affinity of fetal blood (HbF:α2γ2) is due to the inability of gamma chains to bind 2,3-BPG.