Question
In the following type of graph as shown in the image,what is the cause for the shape of the graph for the fetus?
A. High Hemoglobin Concentration
B. High Oxygen Concentration
C. Inability to bind 2,3 DPG
D. All of the above
Show Answer
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Correct Answer » C
Explanation
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Ans:C. Inability to bind 2,3 DPG
Oxygen Dissociation Curve of Maternal versus Fetal is shown in the image.
- Fetal Hemoglobin has higher affinity to O2 so as to obtain O2 from maternal blood in the placenta.
- The high oxygen affinity of fetal blood (HbF:α2γ2) is due to the inability of gamma chains to bind 2,3-BPG.
