Question
Identify the type of pathological process as shown in the histopathological examination of lymph node in the image.
A. Coagulative Necrosis
B. Fat Necrosis
C. Liquefactive Necrosis
D. Caseous Necrosis
Show Answer
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Correct Answer » D
Explanation
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Ans:D.)Caseous Necrosis
Image shows:Caseous necrosis lymph node. There is eosinophilic, amorphous, granular material, while the periphery shows granulomatous inflammation.
CASEOUS NECROSIS.
- Caseous necrosis is found in the centre of foci of tuberculous infections.
- It combines features of both coagulative and liquefactive necrosis.
- Grossly, foci of caseous necrosis, as the name implies, resemble dry cheese and are soft, granular and yellowish.
- This appearance is partly attributed to the histotoxic effects of lipopolysaccharides present in the capsule of the tubercle bacilli, Mycobacterium tuberculosis.
- Microscopically, the necrosed foci are structureless, eosinophilic, and contain granular debris .
- The surrounding tissue shows characteristic granulomatous inflammatory reaction consisting of epithelioid cells with interspersed giant cells of Langhans’ or foreign body type and peripheral mantle of lymphocytes.
