Question
A patient presented with chronic copious cough.History of Smoking is present. Histopathological examination of lung shows the following feature.
Regarding this condition,from the following statements,which is not true?
A. Age at diagnosis is around 50 years.
B. Cor Pulmonale is rare.
C. Dyspnea is late,mild
D. Blue Bloaters
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Correct Answer » B
Explanation
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Ans:B. Cor Pulmonale is rare.
The patient is suffering from Chronic Bronchitis.
CHRONIC BRONCHITIS
MORPHOLOGIC FEATURES.
- Grossly, the bronchial wall is thickened, hyperaemic and oedematous.
- Lumina of the bronchi and bronchioles may contain mucus plugs and purulent exudate.
- Microscopically, just as there is clinical definition, there is histologic definition of chronic bronchitis by increased Reid index. Reid index is the ratio between thickness of the submucosal mucus glands (i.e. hypertrophy and hyperplasia) in the cartilage-containing large airways to that of the total bronchial wall.
- The increase in thickness can be quantitatively assessed by micrometer lens. The bronchial epithelium may show squamous metaplasia and dysplasia.
- There is little chronic inflammatory cell infiltrate.
- The non-cartilage containing small airways show goblet cell hyperplasia and intraluminal and peribronchial fibrosis.
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