A 50 year old male patient presented with a parotid swelling.Histopathological examination of the swelling shows the following features.What can be the most probable diagnosis?
A. Mucoepidermoid Carcinoma
B. Adenoid Cystic Carcinoma
C. Pleomorphic Adenomma
D. Warthin’s Tumor
Ans:B. Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma (Cylindroma)
- This is a highly malignant tumour due to its typical infiltrative nature, especially along the nerve sheaths.
- Adenoid cystic carcinoma is histologically characterised by cribriform appearance i.e. the epithelial tumour cells of duct-lining and myoepithelial cells are arranged in duct-like structures or masses of cells, having typical fenestrations or cyst-like spaces and hence the name ‘adenoid cystic’.
- These cystic spaces contain PAS-positive basophilic material .