Image Based Question-70115

The following type of peripheral blood smear can be seen in which condition?

A. Lead poisoning

B. Macrocytic Anemia

C. Howeell Jolly Bodies

D. Heinz Bodies

Correct Answer » A Explanation

Ans:A. Lead poisoning.

Basophilic Stippling is seen in the peripheral blood smear.

BASOPHILIC STIPPLING.

• Basophilic stippling (punctate basophilia )refers to observing a blood smear in which erythrocytes display small dots at the periphery. These dots are the visualization of ribosomes and can often be found in the peripheral blood smear, even in some normal individuals.

It is associated with several conditions, including:

• Myelodysplastic syndromes

• Sideroblastic anemia

• Lead poisoning (normocytic anemia)

• Arsenic poisoning

• Beta thalassemia

• Alpha thalassemia, HbH Disease

• Hereditary pyrimidine 5′-nucleotidase deficiency

• Thrombotic thrombocytopenic purpura