Image Based Question-70266

Identify this pattern of graft rejection:

A. Hyperacute rejection

B. Acute humoral rejection

C. Acute cellular rejection

D. Chronic rejection

Correct Answer » D Explanation

Ans:D. Chronic rejection.

PATTERNS OF GRAFT REJECTION

A, Hyperacute rejection of a kidney allograft associated with endothelial damage and thrombi in a glomerulus.

B, Acute cellular rejection of a kidney allograft with inflammatory cells in the interstitium and between epithelial cells of the tubules.

C, Acute humoral rejection of a kidney allograft (rejection vasculitis) with inflammatory cells and proliferating smooth muscle cells in the intima.

D, Chronic rejection in a kidney allograft with graft arteriosclerosis. The arterial lumen is replaced by an accumulation of smooth muscle cells and connective tissue in the intima.