Identify this pattern of graft rejection:
A. Hyperacute rejection
B. Acute humoral rejection
C. Acute cellular rejection
D. Chronic rejection
Ans:D. Chronic rejection.
PATTERNS OF GRAFT REJECTION
A, Hyperacute rejection of a kidney allograft associated with endothelial damage and thrombi in a glomerulus.
B, Acute cellular rejection of a kidney allograft with inflammatory cells in the interstitium and between epithelial cells of the tubules.
C, Acute humoral rejection of a kidney allograft (rejection vasculitis) with inflammatory cells and proliferating smooth muscle cells in the intima.
D, Chronic rejection in a kidney allograft with graft arteriosclerosis. The arterial lumen is replaced by an accumulation of smooth muscle cells and connective tissue in the intima.