Question
A patient suffering from long standing GERD presented with difficulty in swallowing solids and liquids.Esophagus shows the following picture.What can be the most probable diagnosis?
A. Squamous Cell carcinoma
B. Adenocarcinoma
C. Barrett’s Esophagus
D. Esophageal Sclerosis
Show Answer
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Correct Answer » B Explanation |
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Ans:B. Adenocarcinoma.
Image shows:Esophageal adenocarcinoma. A, Adenocarcinoma usually occurs distally and, as in this case, often involves the gastric cardia. B, Esophageal adenocarcinoma growing as back-to-back glands.
ESOPHAGEAL ADENOCARCINOMA
- Esophageal adenocarcinoma typically arises in a background of Barrett esophagus and long-standing GERD.
- Esophageal adenocarcinoma occurs most frequently in whites and shows a strong gender bias, being seven times more common in men than in women.
MORPHOLOGY
- Esophageal adenocarcinoma usually occurs in the distal third of the esophagus and may invade the adjacent gastric cardia .
- While early lesions may appear as flat or raised patches in otherwise intact mucosa, tumors may form large exophytic masses, infiltrate diffusely, or ulcerate and invade deeply.
- On microscopic examination, Barrett esophagus frequently is present adjacent to the tumor. Tumors typically produce mucin and form glands