A. Bullous Pemphigoid
B. Pemphigus Vulgaris
C. Dermatitis Herpetiformis
D. Epidermolysis Bullosa
Ans:B. Pemphigus Vulgaris.
- Pemphigus vulgaris is an autoimmune, intraepithelial, blistering disease affecting the skin and mucous membranes. It is mediated by circulating autoantibodies directed against keratinocyte cell surfaces.
- Drugs reported most significantly in association with pemphigus vulgaris include penicillamine, captopril, cephalosporin, pyrazolones, nonsteroidal anti-inflammatory drugs (NSAIDs), and other thiol-containing compounds.
- The diagnosis of pemphigus vulgaris should be considered in any patient with persistent oral erosive lesions.
- Most patients with pemphigus vulgaris develop cutaneous lesions. The primary lesion of pemphigus vulgaris is a flaccid blister, which usually arises on healthy-appearing skin but may be found on erythematous skin.
Differentiating features of major immunobullous diseas