Image Based Question – 73796

Cell growth can be stopped at some specific checkpoints in the cell cycle as depicted. Which stage of cell cycle demonstrates the primary point in regulation of cell growth?

A. End of M

B. End of G1

C. End of S

D. End of G2

Correct Answer » B Explanation

Ans: B. End of G1

(Ref Robbins 9/e p289, 8/e p286)

G1-S:

• End of G1 phase – Primary & most important cell cycle checkpoint.
• Both cell cycle regulators p53 & RB gene act here.