A 17-year-old patient develops intussusception for which he was operated and a segment of intestine showing multiple polyps was resected. Microscopy showed the following pathology. What is the likely diagnosis?
A. Tubulovillous polyps
B. Hamartomatous polyps
C. Inflammatory polyps
Ans: B. Hamartomatous polyps
(Ref Sabiston 20/e p1372, 19/e p1342; Schwartz 10/e p1206 9/e p1042-104:3; Bailey 27/e p12.50. 26/e p1161-1164)
- The given histology shows a large and pedunculated polyp with a firm lobulated contour.
- An arborizing network of connective tissue is seen with well-developed smooth muscle extending into the polyp and surrounding normal abundant glands lined by normal intestinal epithelium rich in goblet cells.
- This is typical of Peutz-Jegher’s polyps, which are a type of hamartomatous polyp.