Image Based Question – 74106

Macrophage engulfs different cells as shown in the image, the process is called:

A. Phagocytosis

B. Emperipolesis

C. Killing

D. Cytotoxicity

Correct Answer » B Explanation

Ans: b. Emperipolesis

(Refi Robbins and Cotran Pathologic Basis of Disease 9^th edn; Page no. 840)

• Emperipolesis is the active penetration of one cell by another which remains intact.
• It differs from phagocytosis in that an engulfed cell exists temporarily within another cell and with an intact normal structure while in phagocytosis, the engulfed cell is destroyed by the protective action of lysosomal enzymes.