Question
A child comes with the history of pain in the right hip and difficulty in walking. X-ray hip was done as seen in the picture. Which of the following is the most likely diagnosis?
A. Osteopetrosis
B. Osteoporosis
C. Osteopoikilocytosis
D. Osteogenesis imperfecta
Show Answer
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Correct Answer » A
Explanation
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Ans: A. Osteopetrosis
(Ref Apley 9/e p166)
- History highly suggestive of osteopetrosis.
Osteopetrosis (Marble Bones, Albers–Schonberg Disease):
- Osteopetrosis is one of several conditions which are characterized by sclerosis and thickening of the bones which appear with increased radiographic density.
- This is the result of an imbalance between bone formation and bone resorption.
- Failed bone resorption due to a defect in osteoclast production and/or function.
