Image Based Question – 74448

In this hematoxylin- and eosin-stained slide of inflammation, identify the cell marked with an arrow:

A. Macrophage

B. Lyrnphocyte

C. Eosinophil

D. Plasnra cell

Correct Answer » D Explanation

Ans: D. Plasnra cell

(Ref: Wintrobes 13/e p303; Robbins 9/e p99.)

• The cell marked with an arrow is plasma cell.
• “Plasma cells are large lymphocytes with a considerable nucleus-to- cytoplasm ratio and a characteristic appearance on light microscopy.
• They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic cartwheel or clock face arrangement.”