Image Based Question – 74578

An area has been marked in the coronal section of the brain below. Defect in this area will lead to what pathology?

A. Alzheimer’s disease

B. Huntington’s chorea

C. Paralysis agitans

D. Dementia

Correct Answer » C Explanation

Answer- C. Paralysis agitans

• The area marked with the star is dark, blackish area in the region of mid-brain, which represents substantia nigra. Lesions of substantia nigra produce Parkinson’s disease, also called paralysis agitans. Paralysis agitans, which literally means “shaking palsy,” is another term used for Parkinson’s disease. In Parkinson’s disease, the levels of dopamine in the substantia nigra and striatum decrease dramatically as a result of the degeneration of pars compacta neurones.