An elderly male patient presented with blurring of vision. Fundus examination revealed cotton wool spots on retina and systemic examination showed decreased peripheral sensations and decreased urine output.
A. Kimmelstiel-Wilson lesion
C. Amyloid deposits
D. Hyaline atherosclerosis
Answer- A. Kimmelstiel-Wilson lesion
- Nodular Glomerulosclerosis. This is also known as inter-capillary glomerulosclerosis or Kimmelstiel-Wilson disease.
- The glomerular lesions take theform of ovoid or spherical, often laminated, nodules of matrix situated in the periphery of the glomerulus. The nodules are PAS-positive. They lie within the mesangial core of the glomeralar lobules and can be surrounded by patent peripheral capillary loops or loops that are markedly dilated.