On histopathological examination of lymph node as shown below. which of the following zone is represented by the marked area?
A. Germinal center
B. Marginal zone
C. Mantle zone
D. Paracortical area
Answer- C. Mantle zone
- The marked structure in histopathological examination of lymph node is mantle zone.
- Mantle zone- Small unchallenged B-cells surrounding pale staining germinal centers
- CD19+ve, CD20+ve, CD10-ve, CD5+ve
- “The mantle zone is produced as surrounding cells are marginalized by the rapidly growing germinal centre.