Question
A 30-year-old male came with complaints of swelling around the knee joint. Histopathological examination of the swelling demonstrated many giant cells interspersed with mononuclear cells. What is the probable diagnosis
A. Osteosarcoma
B. Ewing’s sarcoma
C. Giant cell tumour
D. Chondrosarcoma
Show Answer
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Correct Answer » C
Explanation
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Correct ans: C
GCTs are large and red-brown and often show cystic degeneration.
They are composed of uniform oval mononuclear cells and scattered osteoclast-type giant cells containing 100 or more nuclei.
Mitotic figures are typically frequent.
Necrosis, hemorrhage, and reactive bone formation also are commonly present.
Ref Robbin’s basics of pathology 9th edition page no.781
