Question
True about yθT cells:
A. Are helper t cells
B. Oligoclonal proliferation
C. Antigen presentation
D. Opsonization
Show Answer
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Correct Answer » B Explanation |
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Ans: B. Oligoclonal proliferation
| Cell Type | Subset | Main mediators | Established role | Findings in allergic rhinitis (AR) |
| γδ T cell |
* IFNγ
* IL-17A * IL-17F * IL-22 |
* proinflammatory and immune-modulating functions at epithelial surfaces * innate and adaptive immunity participation |
* yδT cytokines induce B cell IgE synthesis * support Th2 inflammatory response * oligoclonal proliferation in nasal mucosa (?) * ↑ circulating yδT cell percentages correlating with Th17 numbers in AR * negative correlation with Tregs |
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