Allosteric Regulation of enzyme

Allosteric Regulation of enzyme

  • One catalytic site where substrate binds
  • Other site where modifier/ effectors binds

Homotrophic allosteric enzyme- same modulator & substrate. There effect is positive.

Heterotrophic allosteric enzyme- modulator is other than substrate. Can have –ve or +ve effect.

Cooperative Binding – Substrate binding↑ affinity of other substrate  other subunits

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