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Basic principles of pharmacotherapy for depression
- Specific pharmacotherapy doubles the chances of recovery in 1 month
- Most anti-depressants take 3-4 weeks to exert significant therapeutic effects
- Should be taken for 6 months or equal to duration of previous episode [which ever greater]
- Prophylactic advised if >3 episodes in a year or have chronic major depressive disorder [> 2 year]
- Most antidepressants have similar overall efficacy but differ in their SIDE EFFECT Profile
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