Question Fluoroquinolone contraindicated in liver disease is A. Levofloxacin B. Pefloxacin C. Ofloxacin D. Lomefloxacin Show Answer Correct Answer » B Explanation Ans: B. Pefloxacin Pefloxacin has longer t½: accumulates on repeated dosing achieving plasma concentrations twice as high as after a single dose. Because of this, it is effective in many systemic infections as […]
Question Pegloticase is used for the treatment of an Ankylosing spondylosis A. Reactive Arthritis B. CPPD C. Chronic tophaceous gout D. Refractory Rheumatoid arthritis Show Answer Correct Answer » C Explanation Ans: C. Chronic tophaceous gout Pegloticase: Pegloticase is a medication for the treatment of the severe, treatment of refractory chronic gout. It is a
Question Which drug acts via the tyrosine kinase receptor? A. Insulin B. TSH C. LH D. MSH Show Answer Correct Answer » A Explanation Ans: A. Insulin Insulin acts on specific receptors located on the cell membrane of practically every cell, but their density depends on the cell type: liver and fat cells are
Question A patient on lithium therapy developed hypertension. He was started on Thiazide for hypertension. After a few days, he developed coarse tremors and other symptoms suggestive of lithium toxicity. What is the probable mechanism of interaction? A. Thiazide increases the tubular reabsorption of lithium B. Thiazide inhibits the metabolism of lithium C. Thiazides act
Question Mechanism of resistance to penicillins via beta-lactamase is A. Altered penicillin-binding proteins B. Drug efflux C. Breaks drug structure D. Alteration in 50S ribosome structure Show Answer Correct Answer » C Explanation Ans: C. Breaks drug structure β-lactamases are produced by staphylococci, Haemophilus, gonococci, etc. which inactivate penicillin G. The β-lactamases may be present
Question Which of the following antihypertensive drug is avoided in patients with high serum uric acid levels? A. Hydrochlorothiazide B. Enalapril C. Prazosin D. Atenolol Show Answer Correct Answer » A Explanation Ans: A. Hydrochlorothiazide Long-term use of higher dose thiazides in hypertension has caused a rise in blood urate levels. Ref: K. D. Tripathi
Question DOC of prophylaxis for motion sickness – A. Promethazine B. Prochlorperazine C. Metoclopramide D. Itopride Show Answer Correct Answer » A Explanation Ans: A. Promethazine Motion sickness: Antiemetics with the anticholinergic-antihistamine property are the first choice drugs for motion sickness. Antidopaminergic and anti-HT 3 drugs are less effective. All anti-motion sickness drugs act better
Question Which of the following antimicrobials should not be given to a chronic asthmatic patient managed on theophylline therapy? A. Erythromycin B. Amoxicillin C. Cefotaxime D. Cotrimoxazole Show Answer Correct Answer » A Explanation Ans: A. Erythromycin Drugs which inhibit theophylline metabolism and increase its plasma level are Erythromycin, Ciprofloxacin, Cimetidine, Oral contraceptives, Allopurinol; The
Question Theophylline by what mechanism causes diuresis? A. PDE3 inhibition B. PDE4 inhibition C. Beta 2 agonist action D. Adenosine A1 receptor antagonism Show Answer Correct Answer » D Explanation Ans: D. Adenosine A1 receptor antagonism The mildly diuretic actions of both methylxanthines are mainly the result of inhibition of tubular fluid reabsorption along
Question DOC for Onychomycosis? A. Terbinafine B. Fluconazole C. Nystatin D. Itraconazole Show Answer Correct Answer » A Explanation Ans: A. Terbinafine Onychomycosis (a fungal infection of the nail, usually caused by a dermatophyte). Onychomycosis is more difficult to treat than most dermatophytosis because of the inherent slow growth of the nail. Older antifungal agents
