Ketone body utilization

Ketone body utilization

Betahydroxybutrate is converted into 2 molecules of acetyl coA which is further utilized by the body.

he conversion into Acetyl coA consists of following steps:

  1. Betahydroxybutrate is first converted into Acetoacetate
  2. Acetoacetate is converted to Acetoacetyl coA in the presence of thiophorase. Liver does not have thiophorase, hence liver & RBC cannot use ketone bodies.
  3. Acetoacetyl coA is final converted to 2 molecules of Acetyl coA

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