Bile acid synthesis

Bile acid synthesis


BILE ACID SYNTHESIS

  • The primary bile acids are produced from cholesterol in liver.

Primary bile acids are-

  1. Cholic acid
  2. Chenodexycholic acid
  3. glycocholic acid, glycochenodeoxycholic acid, taurocholic acid.
  • Secondary bile acids produced from cholesterol in intestine.

Secondary bile acids are-

  1. Deoxycholic Acid
  2. Lithocholic Acid
  • Cholesterol converted to 7 Hydrocholesterol by 7 α- Hydroxylase.
  • The first and rate limiting step by enzyme 7 α- Hydroxylase.

Exam Important

  • The primary bile acids are produced from cholesterol in liver.

Primary bile acids are-

  1. Cholic acid
  2. Chenodexycholic acid
  3. Glycocholic acid, glycochenodeoxycholic acid, taurocholic acid.
  • Secondary bile acids produced from cholesterol in intestine.

Secondary bile acids are-

  1. Deoxycholic Acid
  2. Lithocholic Acid
  • Cholesterol converted to 7 Hydrocholesterol by 7 α- Hydroxylase.
  • The first and rate limiting step by enzyme 7 α- Hydroxylase.
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