Bile acid synthesis

BILE ACID SYNTHESIS

• The primary bile acids are produced from cholesterol in liver.

Primary bile acids are-

1. Cholic acid
2. Chenodexycholic acid
3. glycocholic acid, glycochenodeoxycholic acid, taurocholic acid.

• Secondary bile acids produced from cholesterol in intestine.

Secondary bile acids are-

1. Deoxycholic Acid
2. Lithocholic Acid

• Cholesterol converted to 7 Hydrocholesterol by 7 α- Hydroxylase.
• The first and rate limiting step by enzyme 7 α- Hydroxylase.

Don’t Forget to Solve all the previous Year Question asked on Bile acid synthesis