Blastomycosis

Blastomycosis


Introduction

  • Chronic infection caused by Blastomyces dermatitidis.

B. dermatitis

  • Dimorphic fungus
  • Grows at room temperature as a white or tan mould
  • Grow within host or at 37°C as budding
  • Round yeast like cells.

Epidemiology

  • Infection is largely confined to the North American continent
  • “North American blastomycosis”.

Mode of transmission

  • Inhalation of fungus.

Characterized by

  • Formation of suppurative and granulontatous lesion in any part of the body

  • Marked predilection for the lung and skin.

Clinical manifestations:

  • Self limited pneumonia
  • Skin lesions
  • Mucous membrane and laryngeal lesions 
  • Pseudoepitheliomatous hyperplasia striking
  • May lead to a mistaken diagnosis of squamous cell carcinoma.

ARDS

  • Osteolytic bone lesions
  • Prostatitis
  • Epididymitis

Note

  • South American Blastomycosis is caused by:
  •  Paracoccidioidiosis brasilliensis.
  • European blastomycosis is caused by:
  • Cryptococcus.
Exam Question
 
  • Blastomycosis is a chronic infection caused by Blastomyces dermatitidis.
  • B. dermatitidisis dimorphic fungi
  • B. dermatitidis yeast like
  • Infection is largely confined to the North American continent
  • “North American blastomycosis”.
  • Clinical manifestations:
  • Self limited pneumonia
  • Skin lesions
Don’t Forget to Solve all the previous Year Question asked on Blastomycosis

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