Degradation of Pyrimidine Nucleotides

Degradation of Pyrimidine Nucleotides


  • Cytosine and Uracil to Beta Alanine — CO2, NH3
  • Thymine and β- aminoisobutyrate — CO2, NH3
  • The end products are highly water soluble.

Exam Important

  1. The end products of pyrimidine catabolism are highly water soluble. E.g. CO2, NH3,  β- aminoisobutyrate, beta alanine.
  2. Pseudouridine is excreted unchanged as it cannot be catabolized in human.
  3. Humans have no enzyme that can catabolise pseudouridine derived from degradation of t-RNA.
  4. There is no energy generated in pyrimidine catabolism.
  5. The end products of pyrimidine catabolism is CO2 and H2O.
Don’t Forget to Solve all the previous Year Question asked on Degradation of Pyrimidine Nucleotides

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