
General Exteroreceptors
GENERAL EXTERORECEPTORS
- A type of “Exteroreceptors”.
- Provide information about external environment.
- Like touch, pressure, temperature, light, sound, taste, & smell.
- Cutaneous mechanoreceptors/Tactile/Touch receptors.
- Subtypes:
- Superficial receptors.
- Deep receptors
Thermoreceptors.
- Subtypes:
- Warmth receptors.
- Cold receptors
Nociceptors.
- Subtypes:
- Thermal nociceptors.
- Mechanical nociceptors.
- Polymodal nociceptors.
- Silent nociceptors.
1. Epicritic sensations:
- Involve finer aspects of touch, pressure, & proprioception.
- Mediated by encapsulated receptors.
Eg:
- Fine-touch
- Two-point discrimination.
- Pallesthesia (Detection of vibration).
- Stereognosis (Recognition of shape).
- Topognosis (Recognition of surface texture).
2. Protopathic sensations:
- Involve pain & temperature sense.
- Mediated by receptors with free nerve endings.
- Protopathic sensations are cruder than epicritic sensations
- Have a protective function of warning of injury.
- General exteroreceptors for epicritic senses.
Classifications of receptors:
1. Based on location (skin proximity).
- Superficial receptors.
- Deep receptors
1a. Superficial receptors:
- Present in epidermis or papillary layer of dermis.
- In glabrous (nonhairy) skin, receptors are,
- Merkel’s disc (slowly adapting)
- Meissner’s corpuscle (rapidly adapting).
- ln hairy skin – Hair follicle receptors.
1b. Deep receptors:
- Present in deeper dermis or in subcutaneous tissues.
- Receptors are same in both hair & nonhairy skin
Eg:
- Ruffini’s end organ (slowly adapting)
- Pacinian corpuscle (Rapidly adapting).
- Whether a tactile receptor senses pressure or vibration depends on whether receptor is fastly adapting or slowly adapting.
- Touch, pressure, & vibration are different forms of same sensation.
- Pressure is felt when force applied on skin is sufficient to reach deep receptors.
- Touch is felt when force is insufficient to reach deep receptors.
- Hence, detected by superficial receptors (Merkel’s disc & Meissner’s corpuscle).
- Vibrations are rhythmic variations in pressure.
- I.e. Rhymic variations of force that reaches deep receptors.
Divisions:
2a. Slowly adapting:
- Examples include, “One each from superficial & deep cutaneous receptors”
- Ruffini’s end organ –
- Meant to detect sustained pressure.
- Useless for vibrations.
- Merkel’s disk –
- Detect two-point discrimination.
2b. Rapidly adapting:
- Examples,
- “One each from superficial & deep cutaneous receptors”
- Pacinian corpuscle –
- Stops discharge in response to sustained pressure.
- Useful to detect vibrations – I.e., when pressure fluctuates rapidly.
- Meissner’s corpuscle –
- Detect surface texture.
- Hence, Higher the rate of receptor adaptation —-> Greater is detectable vibration frequency.
- Generally touch
- By Meissner’s corpuscle (detect surface texture i.e. rough or smooth)
- By Merkel’s disc (detect two-point discrimination).
3b. Deep sensations:
- Pressure (Deep touch) – Detected by Rufini organ.
- Vibrations – Detected by Pacinian corpuscle.
- Detect touch (Superficial sensation)
- Merkel’s disk – Slowly adapting & detect two-point discrimination.
- Meissner’s corpuscle – Rapidly adapting & detect surface texture.
2. Deep cutaneous receptors:
- Detect deep touch, pressure, & Vibration.
- Ruffini’s end organ – Slowly adapting & detect sustained pressure/deep touch.
- Pacinian corpuscle – Rapidly adapting & detect vibrations.
PAIN RECEPTORS/NOCICEPTORS:
- General exteroreceptors for protopathic senses.
- Receptors with free nerve endings.
Four types:
- Thermal nociceptor.
- Mechanical nociceptors.
- Polymodal nociceptors.
- Silent nociceptors.
1a. Thermal nociceptors:
- Detect extreme temperature,.
- I.e. < 50C (cold nociceptors) or >450C (warm nociceptors).
1b. Mechanical nociceptors:
- Respond to intense pressure.
- Both thermal & mechanical nociceptors – free nerve endings of Aδ fibers.
1c. Polymodal nociceptors:
- Are free nerve endings of C-fibers
- Respond to high mechanical, chemical/thermal stimuli.
1d. Silent nociceptors:
- Activated by inflammation.
- Not by noxious stimuli.
TEMPERATURE RECEPTORS/THERMOCEPTORS:
Cold receptors:
- Active between 5°-40°C (maximum sensitivity at 25°C)
Warmth receptors:
- Active between 29°C – 45°C (maximum sensitivity at 45°C).
Relationship between pain & temperature receptors:
- Temperature below 5°C stimulates cold nociceptors.
- Temperature above 45°C stimulates heat nociceptors.
- Hence, temperature < 5 °C or > 45°C causes pain.
- Pain and temperature are carried by Aδ (type III) & C (type IV) sensory neurons.
For pain –
- Aδ (Type III) neuron – Fast pain.
- C (Type IV) neuron – Slow pain.
For temperature
- Aδ (Type III) neuron – Cold.
- C (Type IV) neuron – Both cold & warmth.
GENERAL EXTERORECEPTORS
- Provide information about external environment, like touch, pressure, temperature, light, sound, taste, & smell.
- Cutaneous mechanoreceptors, Thermoreceptors & Nociceptors.
- Superficial & deep receptors.
1b. Thermoreceptors/temperature receptors:
- Warmth receptors & Cold receptors.
1c. Nociceptor/Pain receptors:
- Thermal nociceptors, Mechanical nociceptors, Polymodal nociceptors & Silent nociceptors.
- Epicritic sensations & Protopathic sensations.
Protopathic sensations:
- Involve pain & temperature sense.
- Mediated by receptors with free nerve endings.
1a. Superficial receptors:
- Present in epidermis or papillary layer of dermis.
- In glabrous (nonhairy) skin, receptors are,
- Merkel’s disc (slowly adapting).
- Meissner’s corpuscle (rapidly adapting).
- 1b. Deep receptors:
- Includes Ruffini’s end organ (slowly adapting) & Pacinian corpuscle (Rapidly adapting).
1. Slowly adapting:
- Ruffini’s end organ –
- Meant to detect sustained pressure.
- Useless for vibrations.
2. Rapidly adapting:
- Pacinian corpuscle –
- Useful to detect vibrations.
- Meissner’s corpuscle –
- Detect surface texture.
- By Meissner’s corpuscle (detect surface texture i.e. rough or smooth)
2. Deep sensations:
- Pressure (Deep touch) – Detected by Rufini organ.
- Vibrations – Detected by Pacinian corpuscle.
- Merkel’s disk –
- Slowly adapting & detect two-point discrimination.
- Meissner’s corpuscle –
- Rapidly adapting & detect surface texture.
2. Deep cutaneous receptors:
- Ruffini’s end organ –
- Slowly adapting & detect sustained pressure/deep touch.
- Pacinian corpuscle –
- Rapidly adapting & detect vibrations.
- These are receptors with free nerve endings.
- Thermal nociceptors important subtype.
- Cold & warmth receptors.
- Pain and temperature are carried by Aδ (type III) & C (type IV) sensory neurons.
For temperature:
- C (Type IV) neuron – Both cold & warmth.