H. aegyptius and H. ducreyi

H. ducreyi

Morphology

• Short, Gram-negative, nonmotile rods
• Saftey pin appreance

Culture

• Difficult to culture and require special mediums.

Clinical Manifestations

Chancroid 

• Causes ulcus molle (soft chancre) a tropical venereal disease .
• Painful, soft ulcers with ragged undermined margins develop 1–2 weeks after inoculation (usually seen in prepuce and frenulum in men and vulva, cervix, and perianal area in women)

• The infection locus presents as a painful, readily bleeding ulcer occurring mainly in the genital area.
• Regional lymph nodes are quite swollen.
• Suppurating buboes seen 

Diagnosis

• Identification of the pathogen by means of microscopy and culturing are needed to confirm the diagnosis.
•  School of fish appearance or rail road track appearance 

• Sulfonamides, streptomycin, and tetracyclines.
• H. aegyptius (possibly identical with biovar III of Haemophilus influenzae)
• Causes a purulent conjunctivitis occurring mainly in northern Africa, in particular Egypt.
• A raised incidence of Brazilian purpuric fever, a systemic infection with this organism, has been observed in Brazil in recent years.

H. ducreyi

Morphology

• Saftey pin appreance

Clinical Manifestations

Chancroid 

• Causes ulcus molle (soft chancre) a tropical venereal disease .
• Painful, soft ulcers with ragged undermined margins develop 1–2 weeks after inoculation (usually seen in prepuce and frenulum in men and vulva, cervix, and perianal area in women)
• The infection locus presents as a painful, readily bleeding ulcer occurring mainly in the genital area.
• Regional lymph nodes are quite swollen.
• Suppurating buboes seen 

Diagnosis

• Identification of the pathogen by means of microscopy and culturing are needed to confirm the diagnosis.
• School of fish appearance or rail road track appearance 

H. aegyptius (possibly identical with biovar III of Haemophilus influenzae)

• Causes a purulent conjunctivitis occurring mainly in northern Africa, in particular Egypt.