Hemodialysis and Hemoperfusion

Hemodialysis and Hemoperfusion


Hemodialysis and hemoperfusion.

  • These  are peritoneal  dialysis,  hemodialysis,  hemoperfusion  (resin  or charcol),  hemofltration,  plasmapheresis  and exchange  transfusion.

Hemodialysis:

  • It is  useful  in  poisoning with  alcohol  (ethanol  and  methanol). aspirin  (salicylates) acetone,  atenolol,  acetaminophan,  barbiturates, (phenobarbitone)., chloral hydrate, ethylene  glycol, theophylline.
  • not  useful  in  copper  sulphate, benzodiazepines, organophosphates, kerosene and digitalis poisonings.

Hemoperfusion  (chorcol  or  resin)  :

  • Hemoperfusion is the technique of passing blood through a bed of particles contained within a device to which blood lines and a blood pump are attached. It differs from hemodialysis in that blood comes in direct contact with the membrane coated sorbent particle and not a  continuous dialysis membrane, from plasma pharesis in that no plasma is separated from blood
  • It  is  used  in  acetaminophen,  barbiturate, carbamazepine,  chloral  hydrate,  caffeine, CCl4, chloramphenical,  phenytoin,  procainamide, salicylates,  theophylline,  valproate,  dapsone  and  methotrexate.
  • Poisoning by water soluble drugs such as lithium and chemicals which cause acidosis (methanol, ethylene glycol, salicylate) are best treated with hemodialysis.   

Exam Important

  • Hemodialysis is  useful  in  poisoning with  alcohol  (ethanol  and  methanol). aspirin  (salicylates) acetone,  atenolol,  acetaminophan,  barbiturates, (phenobarbitone)., chloral hydrate, ethylene  glycol, theophylline.
  • Hemoperfusion is the technique of passing blood through a bed of particles contained within a device to which blood lines and a blood pump are attached. It differs from hemodialysis in that blood comes in direct contact with the membrane coated sorbent particle and not a  continuous dialysis membrane, from plasma pharesis in that no plasma is separated from blood
  • It  is  used  in  acetaminophen,  barbiturate, carbamazepine,  chloral  hydrate,  caffeine, CCl4, chloramphenical,  phenytoin,  procainamide, salicylates,  theophylline,  valproate,  dapsone  and  methotrexate.
  • Poisoning by water soluble drugs such as lithium and chemicals which cause acidosis (methanol, ethylene glycol, salicylate) are best treated with hemodialysis.
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