Hyperbilirubenimia

Hyperbilirubenimia


HYPERBILIRUBINEMIAS

JAUNDICE

  • Sclera icterus indicates bilirubin >3mg/dL.
  • Sclera icterus in fetus bilirubin >15mg/dL

 Congenital Hyperbilirubinemia

  • Unconjugated hyperbilirubinemias
  1. Glibert’s disease
  2. Crigler- Najjar syndrome
  3. Physiological Jaundice
  4. Breast Milk Jaundice
  5. Lucey Driscoll Syndrome

Conjugated Hyperbilirubinemias

  • Dubin Johnson’s syndrome- caused due to mutation of gene encoding MRP2.
  • Rotor syndrome- defective bile excretion
  • Benign recurrent intrahepatic cholestatsis
  • Progressive Familial intrahepatic cholestatsis

ACQUIRED HYERBILIRUBINEMIA

  • Hemolytic jaundice
  • Hepatic jaundice
  • Obstructive jaundice 

Exam Important

  • Sclera icterus in fetus bilirubin >15mg/dL

Congenital Hyperbilirubinemia

  • Unconjugated hyperbilirubinemias
  1. Glibert’s disease
  2. Crigler- Najjar syndrome
  • Physiological Jaundice
  • Breast Milk Jaundice
  • Lucey Driscoll Syndrome

Conjugated Hyperbilirubinemias

  • Dubin Johnson’s syndrome- caused due to mutation of gene encoding MRP2.
  • Rotor syndrome- defective bile excretion
  • Benign recurrent intrahepatic cholestatsis
  • Progressive Familial intrahepatic cholestatsis
Don’t Forget to Solve all the previous Year Question asked on Hyperbilirubenimia

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