Interstitial keratitis
INTERSTITIAL KERATITIS
- Inflammation of corneal stroma without primary inflammation of epithelium or endothelium.
Causes:
1. Viral:
- HSV
- Herpes zoster
- EBV
- Mumps, Measles
2. Bacterial:
- TB
- Syphilis
- Lyme disease
- Lymphogranuloma venerum
- Leprosy
3. Other:
- Sarcoidosis
- Cogan’s syndrome
- 90 % cases associated with congenital syphilis
- Usually bilateral in congenital syphilis and unilateral in acquired syphilis
- Hutchinson’s triad: Hutchinson’s teeth, vestibular deafness, interstitial keratitis
CLINICAL FEATURES
- Divided into 3 stages:
1. Initial progressive phase:
- Keratic precipitates (KPs)
- ground glass appearance of cornea
- Pain, lacrimation, photobia
2. Florid stage:
- deep vascularization of cornea
- Salmon patch appearance of cornea
3. Stage of regression:
- ghost vessels in cornea
Exam Question
- Salmon patch appearance of cornea seen in Interstitial Keratitis.
- Interstitial keratitis is commonly seen in Congenital syphilis.
Don’t Forget to Solve all the previous Year Question asked on Interstitial keratitis