Lactic Acidosis

Lactic Acidosis

• In the management of diabetes mellitus, lactic acidosis is commonly caused by Metformin
• Lactic acidosis is seen in  Methanol poisoning, Respiratory failure & Circulatory failure
• Deaths from lactic acidosis in diabetes mellitus is associated with therapy with  Phenformin
• Lactic acidosis is a side effect ofPhenformin & Metformin
• A child presents with metabolic lactic acidosis along with hyperammonemia and convulsion is due to Reye’s syndrome
• Thiamine deficiency lead to lactic acidosis
• Congenital lactic acidosis may occur d/t defect in PDH complex
• True about cause of Lactic Acidosis is that it is mainly caused by intake of Biguanides
• Lactic acidosis causes high anion gap metabolic acidosis 
• Increased anion gap is seen in Lactic acidosis
• Linezolid may cause Lactic acidosis
• Extensive Ileal resection can cause  Lactic acidosis