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Urolithiasis

urolithiasis


UROLITHIASIS

  • Urolithiasis/ nephrolithiasis is the formation of urinary calculi at any level of urinary tract.
  • Most common location of calculi arise in the kidney.
  • More common in males.
  • Seen in 2nd to 3rd decades of life.
  • They are characterised by colicky pain (renal colic) & hematuria.

Types of Urinary Calculi-

  • There are 4 types of urinary calculi-
  • 90% Idiopathic
  • Most common abnormality found in standard investigation – hypercalcemia
  • Calcium oxalate – most common (70%)
  • Struvite stones – 15%
  • Calcium phosphate – 10%

a) Calcium stones-

  • Most common of all calculi
  • Most common cause is hypercalciuria with or without hypercalcemia
  • They are radioopaque stones.

b) Mixed (Struvite) stones-

  • Made up of magnesium- ammonium- calcium phosphate so often called as struvite or triple phosphate stones.
  • Caused due to infection of urinary tract with organism as Proteus so called as infection induced stones.
  • ‘Staghorn stones’ is an example of struvite stone.

c) Uric acid stones-

  • Made of uric acid.
  • They are radiolucent.
  • Caused by hyperuricaemia and hyperuricosuria as primary and secondary gout.
  • Hyperuricosuria is the most important factor for the production ofuric acid stones.

 d) Cystine stones-

  • Formed in acidic urine due to genetic defect of metabolism.
  • They are yellowish and waxy.

Exam Important

  • Gastrointestinal disorders predisposes to urolithiasis -short bowel syndrome.
  • Gallstones and kidney stones are known complications of IBD
  • 90% Idiopathic
  • Most common abnormality found in standard investigation –hypercalcemia
  • Calcium oxalate – most common (70%)
  • Struvite stones – 15%
  • Calcium phosphate – 10%

 

Don’t Forget to Solve all the previous Year Question asked on urolithiasis

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