Vitamin A Deficiency

Vitamin A Deficiency


Vitamin A Deficiency-

  • Xerophthalmia (dry eye)
  • Nyctalopia
  • Conjunctival xerosis
  • Bitot’s spots
  • Keratomalacia
  • Corneal scarring
  • Gonadal dysfunction
  • Follicular hyperkeratosis

 Vitamin A Toxicity (Hypervitaminosis A)

  • Hypervitaminosis A can lead to rupture of lysosomal membrane.
  • Acute toxicity- Pseudotumour cerebri (headache, dizziness, vomiting, drowsiness, blurred vision)
  • Chronic toxicity- anorexia, weight loss, nausea, bone and joint pain, bone abnormalities and bony swelling.

Treatment-

  • 200000 or 110mg of Retinol palmitate orally in 2 days.
  • Single massive dose 100000 IU to children (6 month- 1 year) once in 6 months.
  • Single massive dose 200000 IU to children (1_6 years) once in 6 months
  • Required Daily Allowance of Vitamin A (μg of Retinol

Children (1-6 yrs)- 400 pg/day

  • Men- 600 pg/day
  • Women- 600 pg/day
  • Pregnancy- 800 pg/day
  • Lactation- 950 pg/day
Exam Question
 
  • Clinical manifestations- Xerophthalmia (dry eye), Follicular hyperkeratosis
  • Hypervitaminosis A can lead to rupture of lysosomal membrane.
  • Acute toxicity- Pseudotumour cerebri
  • Chronic toxicity- bone abnormalities and bony swelling.
  •  Single massive dose 100000 IU to children (6 month- 1 year) once in 6 months.
  • Single massive dose 200000 IU to children (1_6 years) once in 6 months
  • Required Daily Allowance of Vitamin A (μg of Retinol)

Children (1-6 yrs)- 400 pg/day

  • Men- 600 pg/day
  • Women- 600 pg/day
  • Pregnancy- 800 pg/day
  • Lactation- 950 pg/day 
Don’t Forget to Solve all the previous Year Question asked on Vitamin A Deficiency

Module Below Start Quiz

Leave a Reply

%d bloggers like this:
Malcare WordPress Security