Question
A pharmacological experiment acted to study the effect of three drugs on heart rate and blood pressure. The following graphs were obtained before and after giving the drug. Which of the following statements is correct?
| A. |
A is isoprenaline
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| B. |
B is epinephrine
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| C. |
C is norepinephrine
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| D. |
Action of C is antagonized by muscarinic blockers
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Show Answer
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Correct Answer � B
Explanation
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Ans: B. B is epinephrine
According to the graph,
- A: Norepinephrine, B: Adrenaline, C: Isoproterenol.
- Action of Isoproterenol is blocked by beta-blockers and not by muscarinic blockers.
Epinephrine:
- One of most potent vasopressor drugs.
Rapid IV infusion of pharmacological dose:
- A Dose-dependent increase in BP.
MOA:
Direct myocardial stimulation by,
- Increases ventricular contraction strength (positive inotropic action).
- Increased heart rate (positive chronotropic action).
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