Which of the following statements is true about the following dose response?
Both A and B are full agonists
B is more potent than A
C is a noncompetitive antagonist
C is a competitive antagonist
Ans: A. Both A and B are full agonists
Given dose response curve:
A & B:
- Full agonists.
- Have maximum possible efficacy.
Details on C drug:
- Not an antagonist.
- it is Partial agonist.
- Drug producing the same response at a lower dose is more potent.
- More DRC towards left –> Greater potency.
- Hence A>B>C>D.