Question
A 40-year-old HIV positive male with unknown CD4+ counts comes in with diarrhea for 3 weeks and intermittent fevers. He is non-compliant with his antiretroviral therapy. Vitals are stable, and examination reveals dry oral mucous membrane. Abdominal exams are unremarkable. He has a normal fundoscopic exam. He is admitted to the hospital for further work-up. CD4+ count is 40 cells/mm3. Clostridium difficile PCR is negative. He is started on intravenous fluid resuscitation, and a colonoscopy is performed, which shows several mucosal ulcerations along the length of the large bowel. Biopsy reveals intracytoplasmic inclusion bodies. What is the next step in the management?
| A. |
IV ganciclovir |
| B. |
IV acyclovir |
| C. |
IV liposomal amphotericin B |
| D. |
Fluconazole |
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