LEIGH’S disease; mitochondrial inheritance
Adrenoleukodystrophy; X-linked recessive inheritance
MELAS; mitochondrial inheritance
Duchene muscular dystrophy; X-linked recessive inheritance
Ans.C.MELAS; mitochondrial inheritance
The pedigree has some distinct features like both males and females being affected but only females could transmit it to the successive generations. This pattern is referred to as maternal transmission which is seen in mitochondrial diseases. As mitochondria are only present in the midpiece of spermatozoa which is not involved in zygote formation (only the head of spermatozoa is fused with the ovum), males do not transmit the deleterious mitochondrial genes to the offspring.