Question
A patient has been diagnosed with Primary Open Angle Glaucoma. On elliciting history, it was observed that the patient is a known case of bronchial asthma. What is the drug of choice for POAG in this patient
| A. |
Latanoprost
|
| B. |
Gemeprost
|
| C. |
Carboprost
|
| D. |
Alprostadil
|
Show Answer
|
Correct Answer � A
Explanation
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|
Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy characterized by an open, normal-appearing anterior chamber angle and a characteristic pattern of optic nerve and visual field damage. Elevated intraocular pressure (IOP) is a major risk factor for the development and progression of the disease.
Latanoprost is a prostaglandin analog that is used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It works by increasing the outflow of aqueous humor from the eye, thereby lowering IOP. It is a first-line treatment for POAG.
Reasons to rule out other options:
B. Gemeprost: This is a prostaglandin analog used in obstetrics to induce abortion or labor.
C. Carboprost: This is a synthetic prostaglandin analog used in obstetrics to control postpartum hemorrhage.
D. Alprostadil: This is a prostaglandin E1 analog used for the treatment of erectile dysfunction and to maintain the patency of ductus arteriosus in neonates with specific congenital heart defects.