Question
A 75 year old female has difficulty in doing activities. She has resting tremors, rigidity, visual hallucination and looking into the sky. Lewy body was seen. Diagnosis is?
| A. |
Parkinson
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| B. |
Alzheimer disease
|
| C. |
Prion disease
|
| D. |
Dementia with Lewy bodies
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Show Answer
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Correct Answer � D
Explanation
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|
Dementia with Lewy Bodies (DLB):
A neurodegenerative disorder with features of Parkinson’s disease & Alzheimer’s disease.
– Core features include:
– Progressive cognitive decline
– Visual hallucinations
– Parkinsonism (tremor, rigidity, bradykinesia)
– Fluctuating cognition (attention & alertness)
– Pathology: Presence of Lewy bodies (alpha-synuclein inclusions) in the cortex & brainstem.
– Patients often have REM sleep behavior disorder & may exhibit a blank stare or “looking into the sky.”
