Mitochondria
Structure & function:
→ Are spherical or cylindrical bodies with 2 lipid bilayer-protein membranes (Outer & Inner membrane)
→ Described as “Powerhouse of cell” – Presence of Enzymes for Energy metabolism & ATP synthesis.
→ Contains independent DNA apart from Nucleus.
→ Functions: Importing & self-synthesizing of Protein.
Metabolic pathways:
→ Fatty Acid Oxidation, Electron Transport Chain (ETC) & Krebs (TCA / Citric acid) cycle & Oxidative Phosphorylation.
→ Urea Cycle & Gluconeogenesis – Initial steps in Mitochondria Later steps in Cytosol.
Mitochondrial enzymes:
Location | Enzyme |
Intra-crystal / Intra-membrane space |
|
Inner Membrane |
|
Mitochondrial Matrix |
|
“MARKER ENZYMES” – Enzymes in Matrix, Inner Membrane & Inter-membrane space