Diffuse Esophageal Spasm

DIFFUSE ESOPHAGEAL SPASM

Q. 1

Intermittent dysphagia is caused by?

1. Stricture
2. Reflux esophagitis
3. Achalasia cardia
4. Pharyngeal diverticulum
5. Diffuse esophageal spasm
 A

1,2 & 3

 B

2,3 & 4

 C

4 & 5

 D

3,4 & 5

Q. 1

Intermittent dysphagia is caused by?

1. Stricture
2. Reflux esophagitis
3. Achalasia cardia
4. Pharyngeal diverticulum
5. Diffuse esophageal spasm
 A

1,2 & 3

 B

2,3 & 4

 C

4 & 5

 D

3,4 & 5

Ans. C

Explanation:

 Intermittent dysphagia   Progressive dysphagia
 
  Diffuse esophageal spasm
  Pharyngeal diverticulum
  Schatzki ring
  Esophagitis  
  Carcinoma esophagus
  Stricture
  Achalasia cardia

Also know:

  • Dysphagia more for solid than liquid implies mechanical obstruction (Ca esophagus, stricture, webs)
  • Dysphagia equal for both solid and liquid from the very onset suggests motor disorder i.e achalasia and diffuse esophageal spasm.

Ref: Harrison 17/e, Page 239; CMDT 2005, Page 546.


Q. 2

Diffuse esophageal spasm is best diagnosed by:

 A

Endoscopy

 B

Manaometry

 C

Barium swallow

 D

CT

Q. 2

Diffuse esophageal spasm is best diagnosed by:

 A

Endoscopy

 B

Manaometry

 C

Barium swallow

 D

CT

Ans. B

Explanation:

Answer is B (Manometry)

Diffuse oesophageal spasm is a type of oesophageal motility disorder. Such Motility disorders are best diagnosed by Manometry studies

`Esophageal manometry is the key test for establishing the diagnosis of diffuse esophageal spasm’ – CSDT

`Esophageal manometry is the only test that distinguishes diffuse esophageal spasm from other primary esophageal motor disorders.

Diffuse Esophageal spasm:

Diffuse Esophageal spasm is a poorly understood hypermotility disorder of the oesophagus

Presentation

–       Symptoms are aggravated by emotional stress, exertion (or related to eating)

Diagnosis

Manometry is the key to establish the diagnosis

The diagnosis is usually made by an esophagogram (Barium swallow) and monometric study

 

 

Esophagogram                                                                                                                         Manometry                                             

(Barium Swallow)

•                                                                                                           Manometry is the key to establish the diagnosis (CSDT)

•  Corkscrew esophagus is classical of Diffuse                         Correlation of subjective complains with evidence of spasm

esophageal spasm (seen in about 30% of cases)                       (induced by vagomimetic drug bethenechol) on manometric

(Radiological evidence of tertiary contractions)                                  studies prvide convincing evidence-Sabiston

•    Esophageal monometry is the only test that distinguishes

diffuse esophageal spasm from other primary esophageal

motor disorders – CSDT

•      An ambulatory motility record (ambulatory manometry) is

preferred over standard manometry as contractions are

intermittent and normal peristalsis is seen in between.

Ambulatory manometry is the single best investigation with a

sensitivity of 90% and specificity of 100%

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