Eye, Endocrine system, Hematopoietic system, CVS and Dermatological system In HIV

Eye, Endocrine system, Hematopoietic system, CVS and Dermatological system In HIV

Q. 1

In a patient with AIDS, which of the following organism is the most common cause of chorioretinitis?

 A

Cytomegalovirus

 B

Toxoplasma gondii

 C

Histoplasma capsulatum

 D

Cryptococcus neoformans

Q. 1

In a patient with AIDS, which of the following organism is the most common cause of chorioretinitis?

 A

Cytomegalovirus

 B

Toxoplasma gondii

 C

Histoplasma capsulatum

 D

Cryptococcus neoformans

Ans. A

Explanation:

CMV retinitis is the most frequent and serious ocular opportunistic infection and is the leading cause of blindness in AIDS patients. 
 
In early stages retinitis may be asymptomatic, but later causes changes in visual acuity, visual field cuts, photophobia, scotoma, and eye redness or eye pain. Indirect ophthalmoscopy shows fluffy white perivascular lesions with areas of hemorrhage within them. Treatment includes intraocular ganciclovir implants, in conjunction with oral ganciclovir. Alternative first-line therapy is ganciclovir without implants for 14 to 21 days.
 
Ref: Harrison’s Internal Medicine, 18th Edition, Chapter 214 ; Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 7th Edition, Chapter 149

 


Q. 2

Ocular manifestation of HIV are:

 A

Predispose to viral, bacterial & fungal function

 B

Kaposi sarcoma

 C

CMV retinitis

 D

All

Q. 2

Ocular manifestation of HIV are:

 A

Predispose to viral, bacterial & fungal function

 B

Kaposi sarcoma

 C

CMV retinitis

 D

All

Ans. D

Explanation:

All


Q. 3

Ocular manifestations in AIDS:

 A

Kaposi sarcoma

 B

Retinitis

 C

Lymphoma

 D

All

Q. 3

Ocular manifestations in AIDS:

 A

Kaposi sarcoma

 B

Retinitis

 C

Lymphoma

 D

All

Ans. D

Explanation:

A i.e. Kaposi sarcoma; B i.e. Retinitis; C i.e. Lymphoma


Q. 4

In a patient with AIDS chorioretinitis is typically caused

 A

Cytomegalovirus

 B

Toxoplasma gondii

 C

Cryptococcus neoformans

 D

Histoplasma capsulatum

Q. 4

In a patient with AIDS chorioretinitis is typically caused

 A

Cytomegalovirus

 B

Toxoplasma gondii

 C

Cryptococcus neoformans

 D

Histoplasma capsulatum

Ans. A

Explanation:

A i.e. Cytomegalovirus

CMV is the most common ocular infection Q as well as most common cause of retinitis in patient of AIDS Q. The classical forms of CMV retinitis is haemorrhagic type, which has been called “Crumbled cheese and ketchup” (sauce & cheese) Q or “pizza pie”, appearance, brush fire appearanceQ and granular form.


Q. 5

Commonest opportunistic organism to cause ocular inflammation in AIDS is

 A

Cytomegalovirus

 B

Herpes simplex virus

 C

Toxoplasmosis

 D

Candida albicans

Q. 5

Commonest opportunistic organism to cause ocular inflammation in AIDS is

 A

Cytomegalovirus

 B

Herpes simplex virus

 C

Toxoplasmosis

 D

Candida albicans

Ans. A

Explanation:

A i.e. Cytomegalovirus

Ocular Involvement In AIDS

  • Earliest & most consistent finding of HIV retinopathy is cotton wool spots Q
  • In AIDS most common ocular infection is CMV chorioretinitisQ
  • Cotton wool spots are most common ophthalmoscopic finding in CMV infection in

AIDS.

  • M.C. cause of chorioretinitis is CMVQ (mostly < 50 cells/mm3 CD4 cell count)
  • Treatment of CMV retinitis is Ganyclovir & FoscanetQ
  • M.C. ocular neoplasm is Kaposi sarcoma

M.C. ocular lesion is microvasculopathy involving conjunctiva & retina.


Q. 6

Chorioretinitis in AIDS is caused by

 A

Candida albicans

 B

Herpes simplex

 C

Toxoplasma

 D

Cytomegalovirus

Q. 6

Chorioretinitis in AIDS is caused by

 A

Candida albicans

 B

Herpes simplex

 C

Toxoplasma

 D

Cytomegalovirus

Ans. D

Explanation:

D i.e.Cytomegalovirus


Q. 7

All of the following ocular lesions may occur in patients suffering from AIDS except

 A

Central toxoplasma chorioretinitis

 B

Central serous retinopathy

 C

CMV retinitis

 D

Candida endophthalmitis

Q. 7

All of the following ocular lesions may occur in patients suffering from AIDS except

 A

Central toxoplasma chorioretinitis

 B

Central serous retinopathy

 C

CMV retinitis

 D

Candida endophthalmitis

Ans. B

Explanation:

Ans. Central serous retinopathy


Q. 8

The commonest ocular infection associated with AIDS is:

 A

Herpes zoster

 B

Ctomegaloviruys

 C

Toxoplasmosis

 D

Tuberculosis

Q. 8

The commonest ocular infection associated with AIDS is:

 A

Herpes zoster

 B

Ctomegaloviruys

 C

Toxoplasmosis

 D

Tuberculosis

Ans. B

Explanation:

Ans Ctomegaloviruys


Q. 9

In a patient with AIDS chorioretinitis is typically caused by:

 A

Cytomegalo virus

 B

Toxoplasma gondi

 C

Cryptococcus neoformans

 D

All of the above

Q. 9

In a patient with AIDS chorioretinitis is typically caused by:

 A

Cytomegalo virus

 B

Toxoplasma gondi

 C

Cryptococcus neoformans

 D

All of the above

Ans. A

Explanation:

Ans. Cytomegalo virus


Q. 10

Ocular manifestations in AIDS:

 A

Kaposi sarcoma

 B

Retinitis

 C

Lymphoma

 D

All

Q. 10

Ocular manifestations in AIDS:

 A

Kaposi sarcoma

 B

Retinitis

 C

Lymphoma

 D

All

Ans. D

Explanation:

Ans. All


Q. 11

Vision loss in HIV is commonly due to infection with:

March 2005 March 2013 (h)

 A

Herpes virus

 B

Toxocara

 C

Toxoplasma

 D

Cytomegalovirus

Q. 11

Vision loss in HIV is commonly due to infection with:

March 2005 March 2013 (h)

 A

Herpes virus

 B

Toxocara

 C

Toxoplasma

 D

Cytomegalovirus

Ans. D

Explanation:

Ans. D: Cytomegalovirus

Cytomegalovirus (CMV) retinitis is a sight-threatening disease frequently associated with Acquired Immunodeficiency Syndrome (AIDS).

Patients with retinitis caused by CMV infection may be asymptomatic or may experience blurred vision, floaters, scotomata, or central or peripheral vision loss or distortion.

Retinal examination shows creamy to yellowish lesions, white granular areas with perivascular exudates, and hemorrhages (“cottage cheese and ketchup”).

The abnormalities initially appear in the periphery, but progress if untreated to involve the macula and optic disc. Vision loss is usually permanent.



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