Lymphogranuloma Venerum

Ans. is ‘c’ i.e., Cell culture 

. “Cell culture is the preferred mode of isolation now. Many cell lines are susceptible but those commonly used are McCoy and HeLa cells”.

Ans. is ‘a’ i.e., Chlamydia trachomatis 

A i.e. Chlamydia trachomatis 

C i.e. LGV

C i.e. LGV

C i.e. LGV

C i.e. LGV

B i.e. LGV

A i.e. Doxycycline

Ans. is ‘a’ i.e. Tuberculosis & ‘c’ i.e. LGV 

Ans. A: Tetracycline

The hallmark of LGV is unilateral or bilateral tender lymphadenopathy that dramatically evolves 2 to 6 weeks after the primary lesion.

The involved lymph nodes increase rapidly in size, and pain and erythema are common. If adjacent to one another, several involved lymph nodes may coalesce. The central areas of such lymph nodes can then undergo necrosis. Fluctuant and suppurative lymph nodes then develop, causing the classic ‘bubo’ of LGV.

The bubo may then rupture and drain purulent material, which is associated with relief from symptoms. The ‘groove sign’ characteristic of LGV is seen if both the inguinal and the femoral nodes are involved.

Tetracycline is the first choice drugs for LGV.

Apart from LGV, tetracyclines are drug of choice for:

• STDs-Chlamydial non-specific urethritis/endocervicitis, granuloma inguinale
• Atypical pneumonia
• Cholera
• Brucellosis
• Plague
• Relapsing fever
• Rickettsial infections-typhus, rocky mountain spotted fever, Q fever etc.

Ans. is ‘b’ i.e., Chlamydia trachomatis

Ans. is ‘a’ i.e., LGV

• Groove sign of Greenblatt’ is pathognomonic of LGV when inguinal lymph nodes are enlarged, they are separated by Poupart’s ligment, producing a groove.