Lymphogranuloma Venerum

Lymphogranuloma Venerum

Q. 1

Most common diagnostic test in LGV is – 

 A

Fluorescent Antibody

 B

Complement fixation test

 C

Cell culture

 D

Frei’s test

Q. 1

Most common diagnostic test in LGV is – 

 A

Fluorescent Antibody

 B

Complement fixation test

 C

Cell culture

 D

Frei’s test

Ans. C

Explanation:

Ans. is ‘c’ i.e., Cell culture 

“Cell culture is the preferred mode of isolation now. Many cell lines are susceptible but those commonly used are McCoy and HeLa cells”.


Q. 2

Lymphogranuloma venerum is caused by – 

 A

Chlamydia trachomatis

 B

Calymmatobacter granulomatis

 C

Haemophilus ducreyii

 D

Treponema pallidum

Q. 2

Lymphogranuloma venerum is caused by – 

 A

Chlamydia trachomatis

 B

Calymmatobacter granulomatis

 C

Haemophilus ducreyii

 D

Treponema pallidum

Ans. A

Explanation:

Ans. is ‘a’ i.e., Chlamydia trachomatis 


Q. 3

LGV is caused by 

 A

Chalamydia trachomatis

 B

Haemophylus ducrei

 C

HTLV type II

 D

Donovanosis granulomatis

Q. 3

LGV is caused by 

 A

Chalamydia trachomatis

 B

Haemophylus ducrei

 C

HTLV type II

 D

Donovanosis granulomatis

Ans. A

Explanation:

A i.e. Chlamydia trachomatis 


Q. 4

Genital ulcer is seen in A/E:

 A

Granuloma inguinale

 B

Syphillis

 C

LGV

 D

Donovanosis

Q. 4

Genital ulcer is seen in A/E:

 A

Granuloma inguinale

 B

Syphillis

 C

LGV

 D

Donovanosis

Ans. C

Explanation:

C i.e. LGV


Q. 5

Bubos with multiple sinuses discharging into inguinal lymph nodes are seen in:

 A

Chancroid

 B

Granuloma Inguinale

 C

LGV

 D

Syphilis

Q. 5

Bubos with multiple sinuses discharging into inguinal lymph nodes are seen in:

 A

Chancroid

 B

Granuloma Inguinale

 C

LGV

 D

Syphilis

Ans. C

Explanation:

C i.e. LGV


Q. 6

Sign of Groove is found in –

 A

Chancroid

 B

Granuloma inguinale

 C

LGV

 D

Syphilis

Q. 6

Sign of Groove is found in –

 A

Chancroid

 B

Granuloma inguinale

 C

LGV

 D

Syphilis

Ans. C

Explanation:

C i.e. LGV


Q. 7

Esthiomine is seen in-

 A

Chancroid

 B

Syphilis

 C

LGV

 D

Gonorrhoea

Q. 7

Esthiomine is seen in-

 A

Chancroid

 B

Syphilis

 C

LGV

 D

Gonorrhoea

Ans. C

Explanation:

C i.e. LGV


Q. 8

Frie test is done in

 A

Donovanosis

 B

LGV

 C

Syphillis

 D

Leprosy

Q. 8

Frie test is done in

 A

Donovanosis

 B

LGV

 C

Syphillis

 D

Leprosy

Ans. B

Explanation:

B i.e. LGV


Q. 9

DOC for LGV

 A

Doxycycline

 B

Ampicillin

 C

Erythromycin

 D

Ceftriaxone

Q. 9

DOC for LGV

 A

Doxycycline

 B

Ampicillin

 C

Erythromycin

 D

Ceftriaxone

Ans. A

Explanation:

A i.e. Doxycycline


Q. 10

Multiple fistula in ano commonly occurs in ‑

 A

Tuberculosis

 B

Gonococcal protocolitis

 C

LGV

 D

a and c

Q. 10

Multiple fistula in ano commonly occurs in ‑

 A

Tuberculosis

 B

Gonococcal protocolitis

 C

LGV

 D

a and c

Ans. D

Explanation:

Ans. is ‘a’ i.e. Tuberculosis & ‘c’ i.e. LGV 


Q. 11

Drug of choice for lymphogranuloma venerum:

March 2005

 A

Tetracycline

 B

Chloramphenicol

 C

Erythromycin

 D

Ampicillin

Q. 11

Drug of choice for lymphogranuloma venerum:

March 2005

 A

Tetracycline

 B

Chloramphenicol

 C

Erythromycin

 D

Ampicillin

Ans. A

Explanation:

Ans. A: Tetracycline

Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by unique serovars of Chlamydia trachomatis (L1, L2, L3) that are unlike those that typically cause urethritis, cervicitis, and proctitis (A-K).

The hallmark of LGV is unilateral or bilateral tender lymphadenopathy that dramatically evolves 2 to 6 weeks after the primary lesion.

The involved lymph nodes increase rapidly in size, and pain and erythema are common. If adjacent to one another, several involved lymph nodes may coalesce. The central areas of such lymph nodes can then undergo necrosis. Fluctuant and suppurative lymph nodes then develop, causing the classic ‘bubo’ of LGV.

The bubo may then rupture and drain purulent material, which is associated with relief from symptoms. The ‘groove sign’ characteristic of LGV is seen if both the inguinal and the femoral nodes are involved.

Tetracycline is the first choice drugs for LGV.

Apart from LGV, tetracyclines are drug of choice for:

  • STDs-Chlamydial non-specific urethritis/endocervicitis, granuloma inguinale
  • Atypical pneumonia
  • Cholera
  • Brucellosis
  • Plague
  • Relapsing fever
  • Rickettsial infections-typhus, rocky mountain spotted fever, Q fever etc.

Q. 12

LGV (lymphogranuloma venerum) is caused by ‑

 A

Treponema pallidum

 B

Chlamydia trachomatis

 C

Calymmatobacter granulomatosis

 D

H Ducreyi

Q. 12

LGV (lymphogranuloma venerum) is caused by ‑

 A

Treponema pallidum

 B

Chlamydia trachomatis

 C

Calymmatobacter granulomatosis

 D

H Ducreyi

Ans. B

Explanation:

Ans. is ‘b’ i.e., Chlamydia trachomatis


Q. 13

Groove sign of greenbalt is seen in ‑

 A

LGV

 B

Donovanosis

 C

Chancroid

 D

Genital Herpes

Q. 13

Groove sign of greenbalt is seen in ‑

 A

LGV

 B

Donovanosis

 C

Chancroid

 D

Genital Herpes

Ans. A

Explanation:

Ans. is ‘a’ i.e., LGV

  • Groove sign of Greenblatt’ is pathognomonic of LGV when inguinal lymph nodes are enlarged, they are separated by Poupart’s ligment, producing a groove.


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