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Marasmus

Marasmus

Q. 1

All are seen in Marasmus except

 A

Hepatomegaly

 B

Muscle wasting

 C

Voracious appetite

 D

Weight loss

Q. 1

All are seen in Marasmus except

 A

Hepatomegaly

 B

Muscle wasting

 C

Voracious appetite

 D

Weight loss

Ans. A

Explanation:

Ans. is ‘a’ i.e., Hepatomegaly

Hepatomegaly is seen in kwashiorkor (not in marasmus).

Marasmus

o It is characterized by gross wasting of muscle and subcutaneous tissues resulting in emaciation and marked stunting.

o There is no edema.

o Body weight is less then 60% of expected.

o Fat in adipose tissues is severely depleted. However the buccal pad of fat is preserved till the malnutrition becomes extreme because a higher proportion of saturated fatty acids is stored there and the saturated fat is the last to be depleted.

o Skin is dry, scaly and inelastic with wrinkles.

o The hair is hypopigmented.

o Abdomen is distended due to wasting and hypotonia of abdominal wall muscles.

o The child is alert but irritable.

o Child may show voracious appetite.


Q. 2

Which of the following is seen in Marasmus and not in Kwashiorkor –

 A

Vocarious appetite

 B

Fatty change in liver

 C

Hypoalbuminem ia

 D

Edema

Q. 2

Which of the following is seen in Marasmus and not in Kwashiorkor –

 A

Vocarious appetite

 B

Fatty change in liver

 C

Hypoalbuminem ia

 D

Edema

Ans. A

Explanation:

Ans. is ‘a’ i.e., Vocarious appetite

Features

Incidence

Stage in PEM

Activity

Muscle wasting

Fat wasting Edema

Weight for height

Appetitite

Skin changes

Hair changes

Anemia

Hepatomegaly

Liver biopsy

Infection

Serum albumin

Insulin level

Others

Recovery

Mortality

Marasmus

More common

Compensated phase

Active Obvious

Severe loss of subcutaneous fat

None

Very low

Vocarious (good) appetite

None

None

Uncommon

Absent

Normal or atrophic

Less prone

Normal or slightly decreased

Normal

Monkey facies

Baggy pant appearance

Early

Less than kwashiorkor

Kwashiorkor Less common

Uncompensated phase

Apathic

Sometimes hidden by edema and fat

Fat often retained but not firm

Present

Low but may be masked by edema

Poor

Diffuse pigmentations, flaky paint dermatosis

Sparse, silky, easily pulled out

Common

Present

Fatty changes

More prone

Low (<3g/100 ml)

Low

Sugar baby appearance

Flag sign of hair

Long time

High in early stage


Q. 3

All of the following conditions are observed in

Marasmus, except –

 A

Hepatomegaly

 B

Muscle wasting

 C

Low insulin levels

 D

Extreme weakness

Q. 3

All of the following conditions are observed in

Marasmus, except –

 A

Hepatomegaly

 B

Muscle wasting

 C

Low insulin levels

 D

Extreme weakness

Ans. A

Explanation:

Ans. is ‘a’ i.e., Hepatomegaly

Changes in body composition in P.E.M.

o Fluid considerations‑

 Total body water in malnourished children is increased to 70-80% of body weight as compared to 60% in age matched well noarished controls.

             Activity of the sodium pump* is reduced.

o Metabolic alterations.

 B.M.R. is reduced by 30% and energy expenditure due to inactivity is very low

             Child may behave like poikilotherm.

o Endocrine changes.

             Insulin levels are reduced (child has glucose intolerance)

             Cortisol and growth hormone levels are increased.

o Cardiovascular system

             Cardiac output and stroke volume are reduced

             Blood pressure is low and renal perfusion is compromised.

o Renal function

             Glomerular.filtration rate and renal plasma flow are reduced in severe P.E.M.

Urinary phosphate and sodium excretion are reduced.

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Q. 4

All are true about marasmus except:   

March 2011

 A

Normal albumin levels

 B

Severe wasting of muscles

 C

Edema

 D

Depleted subcutaneous fat

Q. 4

All are true about marasmus except:   

March 2011

 A

Normal albumin levels

 B

Severe wasting of muscles

 C

Edema

 D

Depleted subcutaneous fat

Ans. C

Explanation:

Ans. C: Edema

Edema is a feature of Kwashiorkar; it ranges from mild to gross, and may represent upto 5-20% of the body weight Remember:

Acute malnutrition is judged by: Weight for height

Chronic malnutrition is judged by: Height for age

Flag sign is seen in Kwashiorkar (hair is thin, brittle, lusterless, sparse, easily pluckable and hypopigmented) Hepatomegaly may be associated with Kwashiorkar


Q. 5

In marasmus wasting is due to ‑

 A

Prolonge dietery deficiency of calori

 B

Prolonge dietery deficiency of protein

 C

Excess catabolism of fat & muscle mass to provide energy

 D

All of above

Q. 5

In marasmus wasting is due to ‑

 A

Prolonge dietery deficiency of calori

 B

Prolonge dietery deficiency of protein

 C

Excess catabolism of fat & muscle mass to provide energy

 D

All of above

Ans. D

Explanation:

Ans. is ‘d’ i.e., All of above

Marasmus

  • Prolonge deficiency of calory & protein due to starvation.
  • Monkey facies- loss of buccal fat.
  • Baggy pants appearance- loose skin of the buttocks hanging down.
  • Loss of axillary fat.
  • Appetite is preserved.
  • No edema.

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