Methyl Alcohol Poisoning
Mechanism of action of ethyl alcohol in methyl alcohol poisoning is:
| A |
Saturate alkaline phosphatase |
|
| B |
Blocks formation of formaldehyde |
|
| C |
Inhibit Ca release |
|
| D |
All of the above |
Mechanism of action of ethyl alcohol in methyl alcohol poisoning is:
| A |
Saturate alkaline phosphatase |
|
| B |
Blocks formation of formaldehyde |
|
| C |
Inhibit Ca release |
|
| D |
All of the above |
Which of the following is not used in methyl alcohol poisoning :
| A |
Gastric lavage |
|
| B |
Dialysis |
|
| C |
Ethyl alcohol |
|
| D |
High does of vitamin B12 |
Which of the following is not used in methyl alcohol poisoning :
| A |
Gastric lavage |
|
| B |
Dialysis |
|
| C |
Ethyl alcohol |
|
| D |
High does of vitamin B12 |
D i.e. High dose vit B12
Best method of treatment of Methyl alcohol poisoning is :
| A |
Calcium gluconate |
|
| B |
Ethyl alcohol |
|
| C |
Amphetamines |
|
| D |
1 % Ammonia |
Best method of treatment of Methyl alcohol poisoning is :
| A |
Calcium gluconate |
|
| B |
Ethyl alcohol |
|
| C |
Amphetamines |
|
| D |
1 % Ammonia |
B i.e. Ethyl alcohol
In methyl alcohol poisoning there is CNS depression, cardiac depression and optic nerve atrophy. These effects are produced due to ‑
| A |
Formaldehyde and formic acid |
|
| B |
Acetaldehyde |
|
| C |
Pyridine |
|
| D |
Acetic acid |
In methyl alcohol poisoning there is CNS depression, cardiac depression and optic nerve atrophy. These effects are produced due to ‑
| A |
Formaldehyde and formic acid |
|
| B |
Acetaldehyde |
|
| C |
Pyridine |
|
| D |
Acetic acid |
Ans. is ‘a’ i.e., Formaldyhyde and formic acid
o Methyl alcohol (methanol) is metabolized to formaldehyde by alcohol dehydrogenase and then to formic acid by aldehyde dehydrogenase. These compounds are responsible for the toxicity. Formic acid can lead to coma and blindness also. Therefore, inhibitor of alcohol dehydrogenase, Femepizole is used for treatment of methanol over dose.
Not true about methyl alcohol poisoning:
AIIMS 13
| A |
Effects are due to formic acid |
|
| B |
Fomepizole competitively inhibits aldehyde dehydrogenase |
|
| C |
Metabolic acidosis |
|
| D |
Blindness |
Not true about methyl alcohol poisoning:
AIIMS 13
| A |
Effects are due to formic acid |
|
| B |
Fomepizole competitively inhibits aldehyde dehydrogenase |
|
| C |
Metabolic acidosis |
|
| D |
Blindness |
Ans. Fomepizole competitively inhibits aldehyde dehydrogenase




