Orotic aciduria
Orotic aciduria is due to deficiency of ‑
| A |
Decarboxylase |
|
| B |
Tyrosinase |
|
| C |
Isomerase |
|
| D |
Homogentisate oxidase |
Orotic aciduria is due to deficiency of ‑
| A |
Decarboxylase |
|
| B |
Tyrosinase |
|
| C |
Isomerase |
|
| D |
Homogentisate oxidase |
Ans. is ‘a’ i.e., Decarboxylase
|
Metabolic disease |
Enzyme deficient |
| Maple syrup urine disease | Branched chain ketoacid dehydrogenase |
| Methyl-melonic aciduria | Methyl-malonyl CoA mutase (isomerase) |
| Isovaleryl-CoA dehydrogenase |
Sweaty feet odor in body |
| Tyrosinemia I (Tyrosinosis) |
Fumarylacetoacetate hydroxylase |
|
Tyrosinemia II |
Tyrosine transaminase (Tyrosine aminotransferase) |
|
Neonatal tyrosinemia |
Hydroxyphenyl pyruvate hydroxylase |
|
Albinism |
Tyrosinase |
|
Alkaptonuria |
Homogentisate oxidase |
| Phenylketonuria |
Phenylalanine hydroxylase |
|
Orotic aciduria Homocystinuria Lesh-Nyhan syndrome Cystinosis |
OMP decarboxylase Cystathionine synthatase Complete deficiency of enzyme HGPRT Cystine reductase |
Orotic aciduria like picture can be produced by deficiency of –
| A |
Vitamin B12 |
|
| B |
Essential fatty acids |
|
| C |
Riboflavin |
|
| D |
None of the above |
Orotic aciduria like picture can be produced by deficiency of –
| A |
Vitamin B12 |
|
| B |
Essential fatty acids |
|
| C |
Riboflavin |
|
| D |
None of the above |
Deficiency of folate or vitamin B12 can cause hematological changes similar to hereditaty ototic aciduria”




