Placenta accreta

Placenta accreta

Q. 1

A 38-year-old woman, gravida 3, para 2, at 32 weeks’ gestation comes to the physician because of bleeding from the vagina. She states that this morning she passed 2 quarter-sized clots of blood from her vagina. Otherwise, she states that she is feeling well. The baby has been moving normally and she has had no contractions or gush of fluid from the vagina. Her obstetrical history is significant for 2 low-transverse cesarean deliveries for non-reassuring fetal heart rate tracings. An ultrasound is performed that demonstrates a complete placenta previa. For which of the following conditions is this patient at highest risk?

 A

Dystocia

 B

Intrauterine fetal demise (IUFD) 

 C

Placenta accreta

 D

Preeclampsia

Q. 1

A 38-year-old woman, gravida 3, para 2, at 32 weeks’ gestation comes to the physician because of bleeding from the vagina. She states that this morning she passed 2 quarter-sized clots of blood from her vagina. Otherwise, she states that she is feeling well. The baby has been moving normally and she has had no contractions or gush of fluid from the vagina. Her obstetrical history is significant for 2 low-transverse cesarean deliveries for non-reassuring fetal heart rate tracings. An ultrasound is performed that demonstrates a complete placenta previa. For which of the following conditions is this patient at highest risk?

 A

Dystocia

 B

Intrauterine fetal demise (IUFD) 

 C

Placenta accreta

 D

Preeclampsia

Ans. C

Explanation:

  • Placenta previa is defined as a placenta located over the cervical os.

There are 3 major types.

Complete previa describes a placenta that completely covers the cervical os.

Partial previa is a placenta that covers some of the cervical os, with the remainder of the os uncovered by the placenta.

Marginal previa describes a placenta that is located at the edge of the cervical os.

Three major risk factors for placenta previa are maternal age, minority race, and previous cesarean delivery.


  • Placenta accreta describes the condition in which there is abnormal attachment of the placenta to the uterine wall.

In this condition, the decidua basalis is absent and the placenta is attached to the myometrium(accreta) or invades into the myometrium (increta) or perforates through the myometrium (percreta).  

Many patients with a previa and accreta will require a hysterectomy at the time of delivery. This patient, with a history of 2 prior cesarean deliveries and a placenta previa is at highest risk for placenta accreta.

  • This patient would not be considered to be at highest risk of dystocia (Choice A) because, with a placenta previa, she would not be allowed to labor and, therefore, would not be at risk of dystocia

Q. 2

All of the following are associated with breech presentation at normal full term pregnancy, except:

 A

Placenta accreta

 B

Fetal malformation

 C

Uterine anomaly

 D

Cornual implantation of placenta

Q. 2

All of the following are associated with breech presentation at normal full term pregnancy, except:

 A

Placenta accreta

 B

Fetal malformation

 C

Uterine anomaly

 D

Cornual implantation of placenta

Ans. A

Explanation:

Ans:A.)Placenta accreta 

 Breech Presentation

The following are the known factors responsible for breech presentation:

  •  Prematurity: It is the most common cause of breech presentation.
  •  Factors preventing spontaneous version: (a) Breech with extended legs, (b) Twins, (c) Oligohydramnios, (d) Congenital malformation of the uterus such as septate or bicornuate uterus, (e) Short cord, relative or absolute, (f ) Intrauterine death of the fetus.
  •  Favorable adaptation: (a) Hydrocephalus—big head can be well accommodated in the wide fundus, (b) Placenta previa, (c) Contracted pelvis, (d) Cornu-fundal attachment of the placenta— minimizes the space of the fundus where the smaller head can be placed comfortably.
  •  Undue mobility of the fetus: (a) Hydramnios, (b) Multiparae with lax abdominal wall.
  •  Fetal abnormality: Trisomies 13, 18, 21, anencephaly and myotonic dystrophy due to alteration of fetal muscular tone and mobility.

 

Placenta accreta

  • It occurs when all or part of the placenta attaches abnormally to the myometrium (the muscular layer of the uterine wall). Three grades of abnormal placental attachment are defined according to the depth of attachment and invasion into the muscular layers of the uterus:
    • Accreta – chorionic villi attach to the myometrium, rather than being restricted within the decidua basalis.
    • Increta – chorionic villi invade into the myometrium.
    • Percreta – chorionic villi invade through the perimetrium (uterine serosa).
  • Complications:
    • (i) damage to local organs (e.g., bowel, bladder, ureters) and neurovascular structures in the retroperitoneum and lateral pelvic sidewalls from placental implantation and its removal; (ii) postoperative bleeding requiring repeated surgery; (iii) amniotic fluid embolism; (iv) complications (e.g., dilutional coagulopathy, consumptive coagulopathy, acute transfusion reactions, transfusion-associated lung injury, acute respiratory distress syndrome, and electrolyte abnormalities) from transfusion of large volumes of blood products, crystalloid, and other volume expanders; and (v) postoperative thromboembolism, infection, multisystem organ failure, and maternal death.


Ref: Textbook of Obstetrics By Dutta


Q. 3

The placenta is anchored to the myometrium par­tially or completely without any intervening decidua is called :

 A

Placenta accreta

 B

Placenta increta

 C

Placenta succenturiate

 D

Placenta percreta

Q. 3

The placenta is anchored to the myometrium par­tially or completely without any intervening decidua is called :

 A

Placenta accreta

 B

Placenta increta

 C

Placenta succenturiate

 D

Placenta percreta

Ans. B

Explanation:

Placenta increta


Q. 4

Treatment of choice in placenta accreta :

 A

Manual removal

 B

Hysterotomy

 C

Hysterectomy

 D

Wait and watch

Q. 4

Treatment of choice in placenta accreta :

 A

Manual removal

 B

Hysterotomy

 C

Hysterectomy

 D

Wait and watch

Ans. C

Explanation:

Hysterectomy


Q. 5

True about placenta accreta is :

 A

Seen in cesarean scar

 B

Removal should be done under GA in piecemeal

 C

Chorionic villi invade serosa

 D

It is an etiological factor for amniotic fluid embo­lism

Q. 5

True about placenta accreta is :

 A

Seen in cesarean scar

 B

Removal should be done under GA in piecemeal

 C

Chorionic villi invade serosa

 D

It is an etiological factor for amniotic fluid embo­lism

Ans. A

Explanation:

Ans. is a i.e. Seen in cesarean scar


Q. 6

Which is not a common cause of Placenta Accreta?

 A

Previous LSCS

 B

Previous currettage

 C

Previous myomectomy

 D

Previous placenta previa/abrupto

Q. 6

Which is not a common cause of Placenta Accreta?

 A

Previous LSCS

 B

Previous currettage

 C

Previous myomectomy

 D

Previous placenta previa/abrupto

Ans. D

Explanation:

Ans. is d i.e. Previous placenta previa / abruptio placenta


Q. 7

Placenta accreta is associated with :

 A

Placenta previa

 B

Uterine scar

 C

Multipara

 D

All of the above

Q. 7

Placenta accreta is associated with :

 A

Placenta previa

 B

Uterine scar

 C

Multipara

 D

All of the above

Ans. D

Explanation:

Ans. :D.)All of the above: a, b and c i.e. Placenta previa; Uterine scar and Multipara.

Placenta accreta

  • It is a type of morbidly adherent placenta, where the placenta is firmly adherent to the uterine wall due to partial or total absence of the decidua basalis and the fibrinoid layer (Nitabuch layer). The main aetiology is defective decidua formation.

Pathological findings

  • Absence of decidua basalis
  • Absence of Nitabuch’s fibrinoid layer
  • Varying degree of penetration of the villi into the muscle bundle.

Classification / variants :

  • Placenta accreta – chorionic villi are attached to the superficial myometrium.
  • Placenta increta – villi invade the myometrium.
  • Placenta percreta – villi penetrate the full thickness myometrium up to the serosal layer.

Risk factors:

  • An important risk factor for placenta accreta is placenta previa in the presence of a uterine scar.
  • Additional reported risk factors for placenta accreta include maternal age and multiparity, other prior uterine surgery, prior uterine curettage, uterine irradiation, endometrial ablation, Asherman syndrome, uterine leiomyomata, uterine anomalies, hypertensive disorders of pregnancy, and smoking.
  • Other risk factors include low-lying placenta, anterior placenta, congenital or acquired uterine defects (such as uterine septa), leiomyoma, ectopic implantation of placenta (including cornual pregnancy).
  • Pregnant people above 35 years of age who have had a Caesarian section and now have a placenta previa overlying the uterine scar have a 40% chance of placenta accreta

Prior to delivery : presumptive diagnosis made by

  • Transvaginal sonography – absence of the subplacental sonoluscent zone(which represents the normal decidua basalis) indicates a placenta accrete.
  • Doppler imaging
  • MRI

Complications:

  • Antepartum haemorrhage (due to associated placenta previa)
  • Uterine rupture before labour (due to myometrial invasion by placental villia at the site of previous C- section scar.
  • Postpartum haemorrhage
  • Infection
  • Inversion of uterus (rare).

Management

In partial morbid adherent placenta

 

 

In total placenta accreta

  • Removal of placental tissue in piecemeal
  • The uterus should be actively contracting.° (So GA is not used)
  • Oxytocics should be used for this purpose
  • Hemostasis should be maintained
  • Complications :

–                Shock

–                Infection

–                Rupture uterus

If female has completed her family

 

Hysterectomy

If female has not completed her family

 

 

Conservative approach :

Cut the umblical cord as high as possible & leave the placenta as such. This is now the most recommended approach. The patient should be given antibiotics & methotrexate in hope of autolysis. R hCG


Q. 8

Common cause of retained placenta :

 A

Atonic uterus

 B

Constriction ring

 C

Placenta accreta

 D

Poor voluntary expulsive effort

Q. 8

Common cause of retained placenta :

 A

Atonic uterus

 B

Constriction ring

 C

Placenta accreta

 D

Poor voluntary expulsive effort

Ans. A

Explanation:

Atonic uterus


Q. 9

Blood is of fetal origin in: 

 A

Placenta previa

 B

Abruptio placentae

 C

Vasa previa

 D

Placenta accreta

Q. 9

Blood is of fetal origin in: 

 A

Placenta previa

 B

Abruptio placentae

 C

Vasa previa

 D

Placenta accreta

Ans. C

Explanation:

Ans. C i.e. Vasa previa



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