Regulators & Factors of Heme Synthesis
Q. 1
Lead inhibits which enzymes in the heme synthesis pathway:
CMC (Vellore) 07
| A |
Aminolevulinate synthase |
|
| B |
Ferrochelatase and 6-ALA dehydratase |
|
| C |
Porphobilinogen deaminase |
|
| D |
Uroporphyrinogen decarboxylase |
Q. 1
Lead inhibits which enzymes in the heme synthesis pathway:
CMC (Vellore) 07
| A |
Aminolevulinate synthase |
|
| B |
Ferrochelatase and 6-ALA dehydratase |
|
| C |
Porphobilinogen deaminase |
|
| D |
Uroporphyrinogen decarboxylase |
Ans.
B
B
Explanation:
Ans. Ferrochelatase and 6-ALA dehydratase
Q. 2
Rate limiting step in heme synthesis is catalyzed by ‑
| A |
ALA dehydratase |
|
| B |
ALA synthase |
|
| C |
UPG decarboxylase |
|
| D |
Ferrochelatase |
Q. 2
Rate limiting step in heme synthesis is catalyzed by ‑
| A |
ALA dehydratase |
|
| B |
ALA synthase |
|
| C |
UPG decarboxylase |
|
| D |
Ferrochelatase |
Ans.
Explanation:
Ans. is ‘b’ i.e., ALA synthase
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