Rotavirus : Classification, Structure, composition and properties

Rotavirus: Classification, Structure, composition and properties

Q. 1

Which of the following statement regarding Rota virus is false?

 A

Most commonly affects children

 B

Double stranded RNA virus

 C

It is a non enveloped virus

 D

None of the above

Q. 1

Which of the following statement regarding Rota virus is false?

 A

Most commonly affects children

 B

Double stranded RNA virus

 C

It is a non enveloped virus

 D

None of the above

Ans. D

Explanation:

Rota virus is a double stranded RNA virus belonging to the family Reoviridae.

The RNA is enclosed in a triple layered, non enveloped icosahedral capsid.

It is one of the commonest cause for watery diarrhoea in children.

Oral rehydration therapy is the most appropriate treatment of choice.


Q. 2

Reassortment has enabled the development of live vaccines, which is a feature of the following virus?

 A

Hepadna virus

 B

Herpes virus

 C

Astrovirus

 D

Rotavirus

Q. 2

Reassortment has enabled the development of live vaccines, which is a feature of the following virus?

 A

Hepadna virus

 B

Herpes virus

 C

Astrovirus

 D

Rotavirus

Ans. D

Explanation:

One unique feature of rotaviruses is the ease with which the 11 RNA segments can undergo reassortment.

Reassortment has enabled the development of live vaccines that combine genes from readily cultivated animal rotaviruses with human rotavirus genes that encode serotype-specific capsid proteins.

Ref: Ray C.G., Ryan K.J. (2010). Chapter 15. Viruses of Diarrhea. In C.G. Ray, K.J. Ryan (Eds), Sherris Medical Microbiology, 5e.


Q. 3

Segmented genome is found in – 

 A

Retrovirus

 B

Rotavirus

 C

Poliovirus

 D

Rhabdovirus

Q. 3

Segmented genome is found in – 

 A

Retrovirus

 B

Rotavirus

 C

Poliovirus

 D

Rhabdovirus

Ans. B

Explanation:

Ans. is b-  Rotavirus


Q. 4

Which of the following is true about Rotavirus ‑

 A

Commonly affects children

 B

Double Stranded DNA

 C

Can be grown easily on cell culture

 D

Egg shell appearance under electron microscope

Q. 4

Which of the following is true about Rotavirus ‑

 A

Commonly affects children

 B

Double Stranded DNA

 C

Can be grown easily on cell culture

 D

Egg shell appearance under electron microscope

Ans. A

Explanation:

Ans. is ‘a’ i.e., Commonly affects children 

.   Rotavirus are now recognized as the most common cause of diarrhea! disease in infants and children.

.  Rotavirus has double stranded RNA

.  Under electron microscope, Rotavirus looks like a wheel.


Q. 5

Genetic reassortment is seen with

 A

Astrovirus

 B

Herpes virus

 C

Rotavirus

 D

Hepadena virus

Q. 5

Genetic reassortment is seen with

 A

Astrovirus

 B

Herpes virus

 C

Rotavirus

 D

Hepadena virus

Ans. C

Explanation:

Ans. is ‘c’ i.e., Rotavirus 

  • The segmented genome of rotavirus allows genetic reassortment during coinfection – a property that may play a role in viral evolution and has been utilized in the development of reassortment animal – human rotavirus – based vaccines.

Q. 6

Double stranded RNA virus with segmented genome‑

 A

Influenza

 B

Rotavirus

 C

Arenavirus

 D

Bunyavirus

Q. 6

Double stranded RNA virus with segmented genome‑

 A

Influenza

 B

Rotavirus

 C

Arenavirus

 D

Bunyavirus

Ans. B

Explanation:

Ans. is ‘b’ i.e., Rotavirus


Q. 7

Double stranded RNA virus ‑

 A

Rotavirus

 B

Measles virus

 C

Mumps virus

 D

Influenza virus

Q. 7

Double stranded RNA virus ‑

 A

Rotavirus

 B

Measles virus

 C

Mumps virus

 D

Influenza virus

Ans. A

Explanation:

Ans. is ‘a’ i.e., Rotavirus



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