Acrodermatitis Enterohepatica

Acrodermatitis Enterohepatica Acrodermatitis enteropathica (AE) It is an autosomal recessive disorder of zinc absorption. It presents in infancy, characterized by a triad of acral dermatitis (face, hands, feet, anogenital area), alopecia, and diarrhea. These infants have a defect in an intestinal zinc transporter, the human ZIP4 protein encoded on the SLC39A4 gene.  Mutations in this gene prevents appropriate […]